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Home / Proteins & Peptide

TRAIL R-2, Human

SKU : BHP18500262

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iXCells Biotechnologies

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Mfr.No.	IX03095, IX03095-1, IX03095-10, IX03095-50
Reconstitution	Reconstituted in ddH2O or PBS at 100 ug/ml.
Description	TRAIL Receptor-2 is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling. The death ligand TRAIL bears high potential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells. TRAIL-R2 is associated with a decrease in the survival rates of breast cancer patients.
Formulation	Lyophilized after extensive dialysis against PBS.
Molecular Weight	~15 kDa, observed by reducing SDS-PAGE.
Source	HEK 293
Host	Human
Accession Number	Q6FH58
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only
Bioactivity	ED50 6 ng/ml, measured in a cell proliferation assay using RPMI-8226 cells in the presence of 25 ng/ml of human TRAIL.

Synonyms	soluble TRAIL Receptor-2, DR5, TNFRSF10B, KILER, TRICK2A, TRICKB
Sequence	ALITQQDLAP QQRAAPQQKR SSPSEGLCPP GHHISEDGRDCISCKYGQDY STHWNDLLFC LRCTRCDSGE VELSPCTTTRNTVCQCEEGT FREEDSPEMC RKCRTGCPRG MVKVGDCTPWSDIECVHKE

Purity	95% as analyzed by SDS-PAGE and HPLC.
Storage	Lyophilized recombinant Human TRAIL Receptor-2 remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Human TRAIL Receptor-2 should be stable up to 1 week at 4°C or up to 2 months at -20°C.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500262-1	IX03095-1	1mg	$711		Add to Cart
BHP18500262-2	IX03095-10	10ug	$49		Add to Cart
BHP18500262-3	IX03095-50	50ug	$107		Add to Cart

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