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Home / Proteins & Peptide

TPH2, His-tag

SKU : BHP18200627

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BPS Bioscience

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Mfr.No.	71193
Description	Human tryptophanhydroxylase 2 (TPH2) also known asneuronal tryptophan hydroxylase,GenBank Accession No. NM_173353, a.a.151-466 (end) with an N-terminal His-tag,MW = 37 kDa, expressed in an E. coli cellexpression system.
Immunogen Region	151-466 (end)
Tag	N-terminal His-tag
Formulation	40 mM Tris-HCl, pH 8.0,110 mM NaCl, 2.2 mM KCl, 0.04%Tween-20, 20% glycerol, and 160 mMimidazole
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	Reaction wasperformed at room temperature in assaybuffer containing 50 mM MOPS, pH 7.0,60 uM tryptophan, 100 mM ammoniumsulfate, 100 uM ferrous ammonium sulfate,0.5 mM TCEP, 0.3 mM 6-methyltetrahydropterin, 0.05 mg/ml catalase, 1mM DTT and TPH2. Fluorescence signalwas measured at Em360nm/Ex300nm. Avoidfreeze/thaw cycles. Storing dilutedenzyme is not recommended, ifnecessary, use carrier protein (BSA 0.1- 0.5%).
GenBank	NM_173353
Mw(kda)	37 kDa

Synonyms	neuronal tryptophan hydroxylase, tryptophan hyrdoxylase 2
Uniprot	Q8IWU9

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Zill, P., et al., Mol. Psychiatr. 2004; 9: 1030-1036. 2. Sheehan, K., et al., Mol. Psychiatr. 2005; 10: 944-949.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200627	71193	50 ug	$368.50		Add to Cart

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