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Home / Proteins & Peptide

TNF-alpha, Rhesus Macaque

SKU : BHP18500450

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Mfr.No.	IX03311, IX03311-1, IX03311-10, IX03311-50
Description	Tumor Necrosis Factor-Alpha (TNF-alpha) plays a major role in regulating growth, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune disease. TNF alpha-1a is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells. In addition to inducing hemorrhagic necrosis of tumors, studies indicate TNF is involved in certain types of tumorigenesis, tumor metastasis, viral replication, septic shock, fever, inflammation, Crohn's disease, rheumatoid arthritis and graft-versus-host disease.Recombinant Rhesus Macaque TNF-alpha produced in E. coli is a single, non-glycosylated polypeptide chain containing 157 amino acids. A fully biologically active molecule, Recombinant Rhesus Macaque TNF-alpha has a molecular mass of 17.4 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
Reconstitution	Reconstituted in ddH2O at 100 ug/ml.
Formulation	Lyophilized after extensive dialysis against PBS
Molecular Weight	17.4 kDa, observed by reducing SDS-PAGE.
Source	E. coli
Accession Number	P48094
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only
Bioactivity	ED50 60 pg/ml, measured in a cytotoxicity assay using mouse L-929 cells in the presence of actinomycin D, corresponding to a specific activity of 1.6 x 107 units/mg.

Synonyms	Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, TNF, TNFA, TNFSF2.
Sequence	Val77-Leu233 (Accession #:P48094)

Purity	95% as analyzed by SDS-PAGEHPLC
Storage	Lyophilized recombinant Rhesus Macaque TNF-alpha, remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Rhesus Macaque TNF-alpha should be stable up to 1 week at 4°C or up to 3 months at -20°C.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500450-1	IX03311-1	1mg	$1686		Add to Cart
BHP18500450-2	IX03311-10	10ug	$75		Add to Cart
BHP18500450-3	IX03311-50	50ug	$200		Add to Cart

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