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Home / Proteins & Peptide

TGFbeta1, Latent

SKU : BHP18201788

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BPS Bioscience

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Mfr.No.	90901-2
Description	Human TGFbeta1 (GenBank Accession No. NM_000660), a.a. 30-390 (end) with Cys33Ser mutation and N-terminal His-tag. Mature latent TGFbeta1 consists of disulfide-linked homodimers of TGFbeta1 latency-associated peptide (LAP) and mature TGFbeta1, MW= ~75 & 25 kDa under non-reducing conditions. host species: human Host species: human Host cell line: FreeStyle 293-F cells
Reconstitution	Reconstitute in sterile 0.2 M acetic acid with 0.1% BSA. Further dilutions may be made in PBS with 0.1% BSA. To maximize product collection from vial surface, vortex briefly and then spin down to recollect the liquid.
Immunogen Region	30-390 (end)
Tag	none
Formulation	Lyophilized from a 0.2 um filtered, aqueous solution
Species	Human
Application	Useful for cell culture and for the study of signaling and apoptotic pathways.
Endotoxin Level	< 1EU per ug
Notes	Avoid freeze/thaw cycles.
Biological Activity Comment	The ED50 measured by TGFbeta1's ability to inhibit mIL-4-dependent proliferation of HT-2 mouse helper T cells is<0.5ng/ml.
GenBank	NM_000660
Mw(kda)	25 kDa

Synonyms	TGFB1, latent transforming growth factor beta 1, LAP, TGFBeta1, TGFbeta1, latency-associated peptide
Uniprot	P01137

Shipping Temperature	gel packs or dry ice
Format	lyophilized protein
Purity	>=98% by SDS-PAGE
Storage	>6 months at -80°C (as a solid). Store reconstituted protein in aliquots at -80°C for up to 3 months. Avoid freeze/thaw cycles.

Reference	1. Derynck, R. et al. (1985). Nature 316(6030):701-5. 2. Bourdrel L., et al. (1993). Protein Expr. Purif. 4:130-140. 3. Munger, J.S., et al. (1997). Kidney Int. 51:1376-1382.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18201788	90901-2	25 ug	$737		Add to Cart

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