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Home / Proteins & Peptide

Sox2-TAT, Human

SKU : BHP18500464

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iXCells Biotechnologies

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Mfr.No.	IX03327, IX03327-50
Description	Sox2 is a member of the Sox family of transcription factors involved in mammalian development containing a highly conserved 79-residue DNA-binding domain, known as the high mobility group (HMG) box. Sox2 is a transcription factor that forms a trimeric complex with Oct4 and binds to DNA to promote the expression of pluripotent genes involved in self-renewal, while repressing genes involved in cell differentiation (ED). Due to its high pluripotency, Sox2 is a commonly used transcription factor for generating induced-pluripotent stem cells (iPSCs). Recombinant Human Sox2-TAT produced in HEK293 cells is a polypeptide chain containing 330 amino acids. The rhSox2-TAT has a molecular mass of 50-55 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
Reconstitution	Reconstituted in ddH2O or PBS at 100 ug/ml.
Formulation	Lyophilized from a 0.2 um filtered solutionin PBS.
Molecular Weight	50-55 kDa, observed by reducing SDS-PAGE.
Source	HEK 293
Accession Number	P02775
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only
Bioactivity	Not Available

Synonyms	MCOPS3; ANOP3; MGC2413; SOX2; SRY (sex determining region Y)-box 2; (SRY)-box 2
Sequence	MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDRVKRPMNAFMV WSRGQRRKMA?QENPKMHNSE ISKRLGAEWK LLSETEKRPFIDEAKRLRAL HMKEHPDYKY RPRRKTKTLM?KKDKYTLPGG LLAPGGNSMASGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY?PQHPGLNAHGAAQMQPMHRY DVSALQYNSM TSSQTYMNGS PTYSMSYSQQGTPGMALGSM?GSVVKSEASS SPPVVTSSSH SRAPCQAGDL RDMISMYLPGAEVPEPAAPS RLHMSQHYQS?GPVPGTAING TLPLSHMGGY GRKKRRQRRR

Purity	95% as analyzed by SDS-PAGE.
Storage	Lyophilized recombinant HumanSox2-TAT remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Human Sox2-TAT should be stable up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500464-1	IX03327-50	50ug	$199		Add to Cart

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