Signal regulatory proteingamma (SIRP-gamma), also known as signal regulatory protein beta 2, and CD172g, GenBank Accession No. NP_018556, a.a. 29-360, fused at the C-terminus to the Fc portion of human IgG1 and Cterminal Avitag, MW 67.6 kDa, expressed in a HEK293 expression system and enzymatically biotinylated using Avitag technology. Note: SIRP-gamma is heavily glycosylated, resulting in higher molecular weight. Biotinylation was confirmed to be>90%.
Immunogen Region
29-360
Tag
C-terminal Fc fusion, C-terminal Avitag
Formulation
8 mM Phosphate, pH 7.4,110 mM NaCl, 2.2 mM KCl, and 20%glycerol
Species
Human
Application
Useful for studying protein binding and screening small molecular inhibitors
Notes
The aggregation state of this product has been confirmed to be<10%. Avoid freeze-thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank
NP_018556
Mw(kda)
67.6 kDa + glycans
Synonyms
Signal regulatory protein-gamma, signal regulatory protein beta 2, and CD172g
Uniprot
Q9P1W8
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Barclay, AN and Brown, MH., Nature Rev. Immunol. 2006; 6: 457-464.