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Home / Proteins & Peptide

SIRP-alpha (CD172a), His-tag

SKU : BHP18200600

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BPS Bioscience

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Mfr.No.	71145
Description	Signal regulatory protein-alpha (SIRP-alpha), also known as Tyrosine-protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1, GenBank Accession No. NP_542970, a.a. 27-370, with C-terminal His-tag, MW 38.4 kDa, expressed in a HEK293 expression system. This protein acts as a receptor for CD47; a.a. 27-370 correspond to the extracellular portion of SIRP-alpha. Note: SIRP-alpha is heavily glycosylated, resulting in apparent higher molecular weight.
Immunogen Region	27-370
Tag	C-terminal His-tag
Formulation	40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.4 mM KCl, and 20% glycerol
Species	Human
Application	Useful for studying protein binding and screening small molecular inhibitors
Notes	The aggregation state of this product has been confirmed to be<10%. Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank	NP_542970
Mw(kda)	38.4 kDa

Synonyms	Tyrosine-protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1
Uniprot	P78324

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Hatherley, D., et al., Mol. Cell, 2008, 31:266-77 2. Baba, N., et al., J. Exp. Med., 2013, 210(6):1251-63

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200600	71145	100 ug	$352		Add to Cart

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