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Home / Proteins & Peptide

Sestrin 2, FLAG-tag

SKU : BHP18200379

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Mfr.No.	50286
Description	Human Sestrin2, also known as hypoxia induced gene 95 (GenBank Accession No. NM_031459), full length, a.a. 2-480(end), with N-terminal FLAG-tag, MW=55 kDa, expressed in Sf9 insect cells via a baculovirus expression system. Host cell line: Sf9 cells
Background	Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. Sestrin 2 is involved in cellular response to different stress conditions and is involved in the reduction of peroxiredoxins.
Immunogen Region	2-480(end)
Tag	N-terminal FLAG-tag
Formulation	45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 3 mM DTT, 90 g/ml FLAG peptide and 10% glycerol.
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	Avoid freeze/thaw cycles.
GenBank	NM_031459
Mw(kda)	55 kDa

Synonyms	Sestrin-2, HI95 SEST2, Hypoxia Induced Gene 95, SES2
Uniprot	P58004

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Lee, J.H., et al. (2010). Science 327(5970): 1223-8. 2. Broderick, G., et al., (2006). Pharmacogenomics 7(3): 407-419. 3. Budanov AV, Karin M. (2008). Cell 134 (3): 451-460. 4. Hay, N. (2008). Cell Metab. 8(3):184-5.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200379	50286	50 ug	$467.50		Add to Cart

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