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Home / Proteins & Peptide

Recombinant Staphylococcus aureus Iron-regulated surface determinant protein B(isdB),partial

SKU : BHP10503341

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP313758SUM
Alternative Names	Fur-regulated protein B, Staphylococcal iron-regulated protein H, Staphylococcus aureus surface protein J, Fur-regulated protein B ; Staphylococcal iron-regulated protein H ; Staphylococcus aureus surface protein J
Antigen	isdB
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Seems to function as the primary receptor for hemoglobin since its inactivation inhibits the ability of S.aureus to bind hemoglobin. Binds hemoglobin in a dose-dependent way. Required for S.aureus growth using hemoglobin as the sole iron source. Also required for virulence. IsdA and/or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity).
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Iron-regulated surface determinant protein B; Alternative name(s): Fur-regulated protein B; Staphylococcal iron-regulated protein H; Staphylococcus aureus surface protein J
Expression Region	41-269aa
Mol Weight	41.6kDa
Nature	recombinant
Protein Description	Partial

Subcellular Location	Secreted, cell wall, Peptidoglycan-anchor
Uniprot	P0C7J5, P0C7J5
Function	Seems to function as the primary receptor for hemoglobin since its inactivation inhibits the ability of S.aureus to bind hemoglobin. Binds hemoglobin in a dose-dependent way. Required for S.aureus growth using hemoglobin as the sole iron source. Also required for virulence. IsdA and/or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity).
Protein Families	IsdB family
Research Area	Microbiology
Weight	41.59kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

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SKU	Supplier No.	Size	Your price	Quantity
BHP10503341	CSB-EP313758SUM	1mg	$2466		Add to Cart
BHP10503341	CSB-EP313758SUM	100ug	$729		Add to Cart
BHP10503341	CSB-EP313758SUM	20ug	$388		Add to Cart

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