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Home / Proteins & Peptide

Recombinant Rat TNF-alpha/TNFA Protein (Active)

SKU : BHP10305838

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSR030443
Alternative Names	Tnf;MGC124630;RATTNF;TNF-alpha;Tnfa
Reconstitution	Please refer to the printed manual for detailed information.
Background	Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.
Reactivity	Rat
Description	A DNA sequence encoding the mature form of rat TNFalpha (P16599) (Leu 80-Leu 235) was expressed and purified, with an initial Met at the N-terminus.
Formulation	Lyophilized from sterile PBS, pH 7.4
Host	E. coli
Accession Number	P16599
Endotoxin Level	Please contact us for more information.
Bioactivity	Measured in a cytotoxicity assay using L929 mouse fibrosarcoma cells in the presence of metabolic inhibitor actinomycin D. The ED50 for this effect is typically 20-80 pg/ml.
Mol Weight	17.4 kDa
Mw(kda)	17.4 kDa

Sequence Info	Leu 80-Leu 235

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 93 % as determined by SDS-PAGE

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305838	PKSR030443	20ug	$281		Add to Cart

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