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Home / Proteins & Peptide

Recombinant Rat Sclerostin/SOST Protein (His Tag)

SKU : BHP10305817

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSR030407
Description	A DNA sequence encoding the rat SOST (NP_085073.1) (Met 1-Tyr 213) was expressed, fused with a polyhistidine tag at the C-terminus.
Alternative Names	SOST
Reconstitution	Please refer to the printed manual for detailed information.
Background	Sclerostin, the protein product of the SOST gene, is a potent inhibitor of bone formation. Sclerostin protein is widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteeoblasts differentiated for 21 days, and was originally identified as an important regulator of bone remodeling, homeostasis, and links bone resorption and bone apposition. Recent studies have revealed that Sclerostin protein inhibits the bone growth probably by binding to the extracellular domain of the Wnt coreceptors LRP5 and LRP6 and disrupting Wnt-induced Frizzled-LRP complex formation.
Reactivity	Rat
Tag	C-His
Formulation	Lyophilized from sterile PBS, pH 7.4
Host	HEK293 Cells
Accession Number	NP_085073.1
Endotoxin Level	< 1.0 EU per ?g of the protein as determined by the LAL method
Mol Weight	23 kDa
Mw(kda)	23 kDa

Sequence Info	Met 1-Tyr 213

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 97 % as determined by SDS-PAGE

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305817	PKSR030407	20ug	$524		Add to Cart

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