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Home / Proteins & Peptide

Recombinant Rat OLR1/LOX1 Protein (Fc Tag)

SKU : BHP10305743

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSR030275
Description	A DNA sequence encoding the rat OLR1 (O70156) (Leu60-Gln364) was expressed with Fc region of human IgG1 at the N-terminus.
Alternative Names	OLR1;Lox1;Oldlr1
Reconstitution	Please refer to the printed manual for detailed information.
Background	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-ligand receptor originally identified as the endothelial oxidized LDL receptor. OLR1 / LOX1 was isolated from an aortic endothelial cell, and recently it has been discovered in macrophages and vascular smooth muscle cells in artery vessels. The expression of LOX1 is inducted by inflammatory stimuli and oxidative stimuli. This protein binds, internalizes and degrades oxidized low-density lipoprotein. LOX1 may play an important role in the progression of vulnerable carotid plaque and might regulate vulnerable plaque formation in cooperation with MMPs and TIMP-2. In clinical, LOX1 is thought to be involved in the development of atherosclerotic lesions.
Reactivity	Rat
Tag	N-Fc
Formulation	Lyophilized from sterile PBS, pH 7.4
Host	HEK293 Cells
Accession Number	O70156
Endotoxin Level	< 1.0 EU per ?g of the protein as determined by the LAL method
Mol Weight	63.9 kDa
Mw(kda)	63.9 kDa

Sequence Info	Leu60-Gln364

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	(90.4+8.5) % as determined by SDS-PAGE

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305743	PKSR030275	100ug	$732		Add to Cart

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