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Home / Proteins & Peptide

Recombinant Rat Nitric oxide synthase, endothelial(Nos3),partial

SKU : BHP10502105

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-RP165794r(A3)
Alternative Names	Constitutive NOS ,cNOSEC-NOSEndothelial NOS ,eNOSNOS type III ,NOSIII, Constitutive NOS ; cNOSEC-NOSEndothelial NOS ; eNOSNOS type III ; NOSIII
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	519-690aa
Mol Weight	22.9kDa
Nature	recombinant
Protein Description	Partial

Subcellular Location	Membrane, caveola, Cytoplasm, cytoskeleton, Golgi apparatus, Cell membrane
Uniprot	Q62600, Q62600
Database Links	KEGG:rno:24600 STRING:10116.ENSRNOP00000013058 UniGene:Rn.44265
Function	Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Pathway	Calcium signaling pathway; Estrogen signaling pathway; HIF-1 signaling pathway; PI3K-Akt signaling pathway; VEGF signaling pathway; Nitric oxide signaling; AGE-RAGE signaling pathway in diabetic complications; Apelin signaling pathway; cGMP-PKG signaling pathway; Sphingolipid signaling pathway
Protein Families	NOS family
Research Area	Others
Tissue Specificity	Expressed constitutively by vascular endothelium. Detected in alveolar and serosal epithelial cells as well as in endothelial cells in one day old rat. In adult lung, detected in rare endothelial cells.
Weight	23kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Rattus Norvegicus (Rat)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10502105	CSB-RP165794r(A3)	1mg	$2466		Add to Cart
BHP10502105	CSB-RP165794r(A3)	100ug	$578		Add to Cart
BHP10502105	CSB-RP165794r(A3)	20ug	$306		Add to Cart

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