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Home / Proteins & Peptide

Recombinant Rat LTBR/TNFRSF3 Protein (His Tag)

SKU : BHP10305765

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSR030340
Description	A DNA sequence encoding the rat LTBR (NP_001008316.1) extracellular domain (Met 1-Ala 218) was expressed, fused with a polyhistidine tag at the C-terminus.
Alternative Names	LTBR
Reconstitution	Please refer to the printed manual for detailed information.
Background	LTBR (lymphotoxin beta receptor (TNFR superfamily, member 3)) is a member of the tumor necrosis factor (TNF) family of receptors. Tumor necrosis factor receptor is a trimeric cytokine receptor that binds tumor necrosis factors. The receptor cooperates with an adaptor protein (such as TRADD, TRAF, RIP), which is important in determining the outcome of the response. LTBR is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. LTBR specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). LTBR and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of this protein can trigger apoptosis. Not only does the LTBR help trigger apoptosis, it can lead to the release of the cytokine interleukin 8. Overexpression of LTBR in HEK293 cells increases IL-8 promoter activity and leads to IL-8 release. It is also essential for development and organization of the secondary lymphoid organs and chemokine release.
Reactivity	Rat
Tag	C-His
Formulation	Lyophilized from sterile PBS, pH 7.4
Host	HEK293 Cells
Accession Number	NP_001008316.1
Endotoxin Level	< 1.0 EU per ?g of the protein as determined by the LAL method
Mol Weight	23 kDa
Mw(kda)	23 kDa

Sequence Info	Met 1-Ala 218

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 96 % as determined by SDS-PAGE

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305765	PKSR030340	100ug	$855		Add to Cart

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