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Home / Proteins & Peptide

Recombinant Rat Granulocyte- Macrophage Colony Stimulating Factor (rrGM-CSF)

SKU : BHP11300484

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Mfr.No.	PR3003
Description	GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity.
Regulatory	RUO
Source	Escherichia coli.
Host	Rat
Endotoxin Level	Less than 1EU/mg of rr GM-CSF as determined by LAL method.
Biological Activity Comment	The ED50 was determined by the dose-dependent stimulation of the proliferation of Murine FDC-P1 cells is < 0.01 ng/ml, corresponding to a specific activity of > 1.0 x 108 units/mg.
Nature	Recombinant

Weight	Recombinant rat GM-CSF is a 14.5 kDa globular protein consisting of 128 amino acids residues.

Description	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20C. Further dilutions should be made in appropriate buffered solutions.
Format	Lyophilized from a 0.2mm filtered solution in PBS, pH 7.4. Sterile Filtered White lyophilized (freeze-dried) powder.
Purity	>98% by SDS-PAGE and HPLC analyses.
Storage	This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.

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SKU	Supplier No.	Size	Your price	Quantity
BHP11300484	PR3003	5μg	$205.56		Add to Cart
BHP11300484	PR3003	20μg	$383.33		Add to Cart

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