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Home / Proteins & Peptide

Recombinant Rat EGFR/ErbB1 Protein (His Tag)(Active)

SKU : BHP10305777

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSR030363
Description	A DNA sequence encoding the rat EGFR (E7CXR8) (Met1-Ser646) was expressed, fused with a polyhistidine tag at the C-terminus.
Alternative Names	EGFR
Reconstitution	Please refer to the printed manual for detailed information.
Background	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
Reactivity	Rat
Tag	C-His
Formulation	Lyophilized from sterile PBS, pH 7.4
Host	HEK293 Cells
Accession Number	E7CXR8
Bioactivity	1. Measured by its ability to bind recombinant human EGF-Fc in a functional ELISA.2. Measured by its ability to bind recombinant mouse EGF-Fc in a functional ELISA.
Mol Weight	70.7 kDa
Mw(kda)	70.7 kDa

Sequence Info	Met1-Ser646

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 98 % as determined by SDS-PAGE

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305777	PKSR030363	100ug	$732		Add to Cart

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