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Home / Proteins & Peptide

Recombinant Rat CD133/PROM1/Prominin 1 Protein (Fc Tag)

SKU : BHP10305732

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSR030231
Description	A DNA sequence encoding the rat PROM1 (NP_001103607.1) (Asn171-Tyr424) was with the Fc region of mouse IgG1 at the N-terminus.
Alternative Names	PROM1
Reconstitution	Please refer to the printed manual for detailed information.
Background	CD133, also known as PROM1 and Prominin 1, is a pentaspan transmembrane glycoprotein which belongs to the prominin family. It localizes to membrane protrusions and is often expressed on adult stem cells. CD133 is known to play a role in maintaining stem cell properties by suppressing differentiation. CD133 binds cholesterol in cholesterol-containing plasma membrane microdomains. It is proposed to play a role in apical plasma membrane organization of epithelial cells. CD133 is also involved in regulation of MAPK and Akt signaling pathways. Mutations in PROM1 gene have been shown to result in retinitis pigmentosa and Stargardt disease. PROM1 gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Expression of this gene is also associated with several types of cancer.
Reactivity	Rat
Tag	N-Fc
Formulation	Lyophilized from sterile PBS, pH 7.4
Host	HEK293 Cells
Accession Number	NP_001103607.1
Endotoxin Level	< 1.0 EU per ?g of the protein as determined by the LAL method
Mol Weight	55.1 kDa
Mw(kda)	55.1 kDa

Sequence Info	Asn171-Tyr424

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	(79.2+14.5) % as determined by SDS-PAGE

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305732	PKSR030231	100ug	$855		Add to Cart

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