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Recombinant Rabies virus Glycoprotein(G),partial

SKU : BHP10504039

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-BP325676RAF
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells (By similarity).
Source	Baculovirus
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Expression Region	20-459aa
Mol Weight	51.5 kDa
Nature	recombinant
Protein Description	Partial

Subcellular Location	Virion membrane, Single-pass type I membrane protein
Uniprot	P19462, P19462
Function	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells (By similarity).
Protein Families	Lyssavirus glycoprotein family
Research Area	Microbiology
Weight	50.29kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 85% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Storage Buffer	Tris-based buffer,50% glycerol

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SKU	Supplier No.	Size	Your price	Quantity
BHP10504039	CSB-BP325676RAF	1mg	$2980		Add to Cart
BHP10504039	CSB-BP325676RAF	100ug	$1322		Add to Cart
BHP10504039	CSB-BP325676RAF	20ug	$472		Add to Cart

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