Recombinant Pig Transcobalamin-1(TCN1)

Mfr.No.	CSB-YP023317PI
Alternative Names	CobalophilinHaptocorrin,Protein RTranscobalamin I ,TC I ,TCI, CobalophilinHaptocorrin ; Protein RTranscobalamin I ; TC I ; TCI
Antigen	TCN1
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Binds vitamin B12 with ftomolar affinity and protects it from the acidic environment of the stomach . Binds to cobalamin and to cobalamin analogs such as cobinamide.
Source	Yeast
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Transcobalamin-1; Short name= TC-1; Alternative name(s): Cobalophilin; Haptocorrin; Protein R; Transcobalamin I; Short name= TC I; Short name= TCI
Expression Region	25-416aa
Mol Weight	46.3kDa
Nature	recombinant
Protein Description	Full Length of Mature Protein

Subcellular Location	Secreted
Uniprot	P17630, P17630
Database Links	UniGene:Ssc.16234
Function	Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach (By similarity). Binds to cobalamin and to cobalamin analogs such as cobinamide.
Protein Families	Eukaryotic cobalamin transport proteins family
Research Area	Others
Tissue Specificity	Haptocorrins are a family of cobalamin-binding glycoproteins found in blood, salivary and mucosal secretions.
Weight	46.3kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol