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Home / Proteins & Peptide

Recombinant PDGF-BB, Human (P. pastoris-expressed)

SKU : BHP11300300

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Mfr.No.	BK0343‐10μg
Description	Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle, connective tissue, bone and cartilage cells, and some blood cells. The PDGF is involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. PDGF which is composed of a dimer of two chains termed the A chain and B chain, can be present as AA or BB homodimers or as an AB heterodimer.Recombinant human Platelet-Derived Growth Factor-BB (rhPDGF-BB) produced in Pichia pastoris is a glycosylated polypeptide. rhPDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids) and is obtained by proprietary chromatographic techniques at GenScript.
Alternative Names	PDGF
Regulatory	RUO
Source	P. pastoris
Host	Human
Endotoxin Level	<1.0 EU/μg, determined by LAL method.
Biological Activity Comment	ED50 <3 ng/ml, measured by the dose-dependent stimulation of the proliferation of Balb/c 3T3 cells, corresponding to a specific activity of >3.3 x 10ˆ5 units/mg.
Nature	Recombinant

Weight	24.3kDa, observed by non-reducing SDS-PAGE.

Description	Reconstituted in ddH2O at 100 μg/ml.
Format	Lyophilized after extensive dialysis against 10mM acetic acid. Sterile Filtered White lyophilized (freeze-dried) powder.
Purity	> 97% by SDS-PAGE and HPLC analyses.
Storage	Lyophilized recombinant human Platelet-Derived Growth Factor-BB (rhPDGF-BB) remains stable up to 12 months at -80°C from date of receipt. Upon reconstitution, rhPDGF-BB should be stable up to 4 weeks at 4°C or up to 6 months at -20°C.

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SKU	Supplier No.	Size	Your price	Quantity
BHP11300300	BK0343‐10μg	10μg	$252.67		Add to Cart

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