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Home / Proteins & Peptide

Recombinant Mouse Spermine oxidase(Smox)

SKU : BHP10500928

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP021844MO
Alternative Names	Polyamine oxidase 1 ,PAO-1 ,PAOh1, Polyamine oxidase 1 ; PAO-1 ; PAOh1
Antigen	Smox
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal.
Source	E.coli
Abbreviation	Smox
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Spermine oxidase; EC= 1.5.3.16; Alternative name(s): Polyamine oxidase 1; Short name= PAO-1; Short name= PAOh1
Expression Region	1-555aa
Mol Weight	77.9kDa
Nature	recombinant
Protein Description	Full Length

Subcellular Location	Cytoplasm, SUBCELLULAR LOCATION: Isoform 2: Cytoplasm, Nucleus
Uniprot	Q99K82, Q99K82
Database Links	KEGG:mmu:228608 UniGene:Mm.136586
Function	Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal.
Protein Families	Flavin monoamine oxidase family
Research Area	Others
Tissue Specificity	Widely expressed. Isoform 1 and isoform 2 are expressed at higher level in brain and skeletal muscle. Isoform 7 is found in brain and spleen, isoform 10 is widely expressed but found at lower level in heart, kidney, liver and lung.
Weight	77.81kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Mus Musculus (Mouse)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10500928	CSB-EP021844MO	1mg	$2466		Add to Cart
BHP10500928	CSB-EP021844MO	100ug	$578		Add to Cart
BHP10500928	CSB-EP021844MO	20ug	$306		Add to Cart

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