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Home / Proteins & Peptide

Recombinant Mouse PKC delta/PRKCD Protein (His & GST Tag)(Active)

SKU : BHP10305029

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSM040304
Description	A DNA sequence encoding the mouse PRKCD isoform 1 (P28867-1) (Met 1-Ile 674) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
Alternative Names	AI385711;D14Ertd420e;Pkcd;PKCdelta;PKC[d
Reconstitution	Please refer to the printed manual for detailed information.
Background	PRKCD, a novel member of the pkc gene family, maps to human chromosome 3.Protein kinase C (PKC) delta (PRKCD) is a member of the novel PKC subfamily that regulates gene expression in bovine trophoblast cells.Protein kinase Cdelta (PRKCD) initiates this process by phosphorylating FBXO25 and HAX-1, thereby spatially directing nuclear FBXO25 to mitochondrial HAX-1.PRKCD may suppress macroautophagy/autophagy, a cytoprotective mechanism, to promote kidney tubule cell death during cisplatin treatment. Interestingly, PRKCD may do so by phosphorylating AKT, which further phosphorylates MTOR to repress ULK1.
Reactivity	Mouse
Tag	N-His-GST
Formulation	Supplied as sterile 20mM Tris, 500mM NaCl, pH 8.0
Host	Baculovirus-Insect Cells
Accession Number	P28867-1
Endotoxin Level	< 1.0 EU per ?g of the protein as determined by the LAL method.
Bioactivity	Kinase activity untested
Mol Weight	106 kDa
Mw(kda)	106 kDa

Sequence Info	Met 1-Ile 674

Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stotage Note	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Purity	> 93 % as determined by SDS-PAGE

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305029	PKSM040304	50ug	$569		Add to Cart

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