PIM3 or pim-3 oncogene belongs to a family of protooncogenes that encode serine/threonine protein kinases . Pim-3 expressed in hepatocellular carcinoma development and plays a main role in the proliferation of human hepatoma cell lines . Pim-3 also expressed in human pancreatic cancer cell and phosphorylates BAD to block Bad-mediated apoptosis in human pancreatic cancer cell lines (3).
For research use only. Not for diagnostic or therapeutic use.
Accession Number
NM_145478
Bioactivity
The specific activity of PIM3 was determined to be 785 nmol /min/mg as per activity assay protocol.
Gene Name
PIM3
Purity
70% - 90%
Storage
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.