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Recombinant Mouse Leukocyte immunoglobulin-like receptor subfamily B member 3(Lilrb3),partial

SKU : BHP10502377

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-YP012941MO
Alternative Names	Cell-surface glycoprotein p91,Paired immunoglobulin-like receptor B ,PIR-B, Cell-surface glycoprotein p91 ; Paired immunoglobulin-like receptor B ; PIR-B
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
Source	Yeast
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Leukocyte immunoglobulin-like receptor subfamily B member 3; Short name= LIR-3; Short name= Leukocyte immunoglobulin-like receptor 3; Alternative name(s): Cell-surface glycoprotein p91; Paired immunoglobulin-like re
Expression Region	664-841aa
Mol Weight	21.6kDa
Nature	recombinant
Protein Description	Partial

Subcellular Location	Cell membrane, Single-pass type I membrane protein
Uniprot	P97484, P97484
Database Links	KEGG:mmu:18733 STRING:10090.ENSMUSP00000077546 UniGene:Mm.326531
Function	May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
Research Area	Others
Tissue Specificity	Detected in macrophages, splenocytes and B lymphocytes (at protein level). Detected in macrophages, mast cells, splenocytes, peritoneal cells and natural killer cells.
Weight	21.6kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Mus Musculus (Mouse)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10502377	CSB-YP012941MO	500ug	$1593		Add to Cart
BHP10502377	CSB-YP012941MO	100ug	$576		Add to Cart
BHP10502377	CSB-YP012941MO	20ug	$306		Add to Cart

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