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Home / Proteins & Peptide

Recombinant Mouse JNK1 (N-GST tag)

SKU : BHP10901234

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z600014
Description	JNK1 is a member of the MAP kinase group that is activated by dual phosphorylation at thr and tyr residues during exposure to stress such as UV irradiation. JNK1 binds to the c-Jun transactivation domain and phosphorylates it on Ser-63 and Ser-73 . JNK1 has been shown to play an important role in disease processes. Activation of JNK1 results in defects in myotube viability and integrity leading to dystrophic myofiber destruction . JNK1 activity is also abnormally elevated in obesity and removal of JNK1 results in decreased adiposity and significantly improved insulin sensitivity.
Alternative Names	JNK; PRKM8; SAPK1; AI849689; JNK1A2; JNK21B1/2
Appearance	Liquid
Formulation	50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Molecular Weight	71.0 kDa
Quantity	10 µg
Source	Insect cells
Usage	For research use only. Not for diagnostic or therapeutic use.
Accession Number	NM_016700
Bioactivity	The specific activity of JNK1 was determined to be 93 nmol /min/mg as per activity assay protocol.

Gene Name	JNK1

Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901234	Z600014	10µg	$314.44		Add to Cart

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