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Home / Proteins & Peptide

Recombinant Mouse IL6

SKU : BHP10900998

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z200177
Description	IL6 is produced by many different cell types. The main sources in vivo are stimulated monocytes, fibroblasts, and endothelial cells. Macrophages, T cells and B-lymphocytes, granulocytes, smooth muscle cells, eosinophils, chondrocytes, osteoblasts, mast cells, glial cells, and keratinocytes also produce IL6 after stimulation. IL6 is a member of a family of cytokines, which also includes LIF, CNTF, Oncostatin M, IL11, and CT-1. All known members of the IL6 cytokine family induce hepatic expression of acute phase proteins. The IL6 receptor is expressed on T cells, mitogen-activated B cells, peripheral monocytes and some macrophage and B cell derived tumor cell types. It is not expressed in resting B cells but in resting T cells. The IL6 receptor, designated CD126, is a strongly glycosylated protein of 80 kDa. Recombinant Mouse IL6 is a 22 kDa polypepdtide with two intramolecular disulfide bridges.
Alternative Names	B-cell hybridoma growth factor ; Interleukin HP-1 ; IL-6
Quantity	100 µg
Regulatory	RUO
Source	E. coli
Host	Mouse
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method
Biological Activity Comment	The ED50 as determined by the dose-dependent proliferation of murine hybridoma was <0.05ng/ml.

Weight	22.0 kDa

Description	A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Format	Lyophilized Powder Lyophilized from a 0.2 μm filtered solution in PBS
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Immunogen Species	Mus Musculus (Mouse)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900998	Z200177	100µg	$1295		Add to Cart

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