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Home / Proteins & Peptide

Recombinant Mouse IL1RL1/ST2 Protein (Fc Tag) (Active)

SKU : BHP10305305

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSM041051
Description	Recombinant Mouse Interleukin-1 receptor-like 1 is produced by our Mammalian expression system and the target gene encoding Ser27-Ala337 is expressed with a Fc tag at the C-terminus.
Alternative Names	Interleukin-1 receptor-like 1; Lymphocyte antigen 84; Protein ST2; Protein T1; Il1rl1; DER4; Fit-1; IL-1 R4; IL-1RL1; IL-33R; Ly84; ST2L; ST2V; suppression of tumorigenicity 2
Reconstitution	Please refer to the printed manual for detailed information.
Background	ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes. This receptor is very similar to the IL-1 receptor type I and the IL-18 receptor alpha chain in that ST2 also has three extracellular Ig domains and an intracellular Toll domain. ST2 binds IL-33, enhances inflammatory cytokines by activating nuclear factor-?B (NF-?B) and mitogen activated protein (MAP) kinases. ST2 exists as either a membrane bound form (ST2L) or as a soluble form (sST2). ST2L acts as a transmembrane signalling receptor for IL-33 by mediating the effect of IL-33 on the inflammatory process, while sST2 can suppress IL-33 activity.
Reactivity	Mouse
Tag	C-Fc
Formulation	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Host	Human Cells
Accession Number	P14719-2
Endotoxin Level	< 1.0 EU per ?g as determined by the LAL method.
Bioactivity	Immobilized Mouse IL-33(Cat: PKSM041090) at 5ug/ml(100 ul/well) can bind Mouse ST2-Fc. The ED50 of Mouse ST2-Fc is 5ug/ml .
Mol Weight	62.7 kDa
Mw(kda)	62.7 kDa

Sequence Info	Ser27-Ala337

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by SDS-PAGE

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305305	PKSM041051	10ug	$117		Add to Cart
BHP10305305	PKSM041051	50ug	$297		Add to Cart

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