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Home / Proteins & Peptide

Recombinant Mouse IL13RA1 Protein (His Tag)(Active)

SKU : BHP10305184

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSM040873
Description	A DNA sequence encoding the extracellular domain (Met 1-Thr 340) of mouse IL13Ralpha1 (NP_598751.3) precursor was fused with the a polyhistidine tag at the C-terminus.
Alternative Names	AI882074;CD213a1;IL-13r[a
Reconstitution	Please refer to the printed manual for detailed information.
Background	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. IL13RA1/IL-13RA1 serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. IL13RA1/IL-13RA1 binds with low affinity to interleukin-13 (IL13). This subunit together with IL4RA can form a functional receptor for IL13. IL13RA1/IL-13RA1 also serves as an alteate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
Reactivity	Mouse
Tag	C-His
Formulation	Lyophilized from sterile PBS, pH 7.4
Host	HEK293 Cells
Accession Number	NP_598751.3
Endotoxin Level	< 1.0 EU per ?g of the protein as determined by the LAL method.
Bioactivity	1.Measured by its binding ability in a functional ELISA.2.Immobilized mouse IL13RA1-His at 10ug/mL (100uL/well) can bind human Fc-IL13, the EC50 of human Fc-IL13 is 0.5-1.5 ug/mL.
Mol Weight	37.6 kDa
Mw(kda)	37.6 kDa

Sequence Info	Met 1-Thr 340

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 98 % as determined by SDS-PAGE

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305184	PKSM040873	50ug	$454		Add to Cart

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