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Home / Proteins & Peptide

Recombinant Mouse IL-6 Receptor Subunit alpha/IL-6RA/CD126 (C-6His)

SKU : BHP10305666

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSM041429
Description	Recombinant Mouse Interleukin-6 receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Leu20-Pro364 is expressed with a 6His tag at the C-terminus.
Alternative Names	Interleukin-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6R 1; Membrane glycoprotein 80; gp80; CD126
Reconstitution	Please refer to the printed manual for detailed information.
Background	Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part of the receptor for interleukin 6 cytokine. IL6Ra binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitates an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer.
Reactivity	Mouse
Tag	C-6His
Formulation	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Host	Human Cells
Accession Number	P22272
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	38.9 kDa
Mw(kda)	38.9 kDa

Sequence Info	Leu20-Pro364

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	>95% as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305666	PKSM041429	10ug	$270		Add to Cart
BHP10305666	PKSM041429	50ug	$808		Add to Cart

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