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Home / Proteins & Peptide

Recombinant Mouse High affinity immunoglobulin epsilon receptor subunit alpha(Fcer1a)

SKU : BHP10505908

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-CF008532MO
Description	Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Alternative Names	Fc-epsilon RI-alpha
Tag	N-terminal 10xHis-SUMO-tagged
Regulatory	RUO
Relevance	Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Source	in vitro E.coli expression system
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Fc-epsilon RI-alpha
Expression Region	24-250aa
Mol Weight	44.7kDa
Nature	Recombinant
Protein Description	Full Length of Mature Protein

Subcellular Location	Cell membrane, Single-pass type I membrane protein
Uniprot	P20489, P20489
Database Links	KEGG:mmu:14125 STRING:10090.ENSMUSP00000056882 UniGene:Mm.5266
Function	Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Pathway	Fc epsilon RI signaling pathway; Oxidative Phosphorylation; Phospholipase D signaling pathway; Sphingolipid signaling pathway
Research Area	Immunology
Tissue Specificity	Expressed in bone marrow mast cells, as well as in the pineal gland at night.
Weight	44.7 kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Mus Musculus (Mouse)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10505908	CSB-CF008532MO	100ug	$3270		Add to Cart
BHP10505908	CSB-CF008532MO	20ug	$1928		Add to Cart

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