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Home / Proteins & Peptide

Recombinant Mouse FER (N-GST tag)

SKU : BHP10900777

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z600012
Description	FER is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. FER plays a role in regulating cytoskeletal rearrangements and inside out signalling that accompany receptor ligand, cell matrix and cell cell interactions . Genetic analysis using transgenic mouse models implicate FER in the regulation of inflammation and innate immunity. Fer-deficient mice displayed enhanced recruitment of leukocytes in response to local LPS challenge. FER is required for cell-cycle progression in malignant cells. Decreasing the level of FER using RNAi impeded the proliferation of prostate and breast carcinoma cells and led to their arrest at the G0/G1 phase .
Alternative Names	Fert ; Fert2 ; AV082135 ; C330004K01Rik
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Mouse
Biological Activity Comment	The specific activity of FER was determined to be 655 nmol/min/mg as per activity assay protocol.

Weight	59.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Mus Musculus (Mouse)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900777	Z600012	10µg	$314.44		Add to Cart

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