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Home / Proteins & Peptide

Recombinant Mouse Fas apoptotic inhibitory molecule 3(Fcmr) ,partial

SKU : BHP10500526

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP007972MO
Alternative Names	Regulator of Fas-induced apoptosis Toso
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	May play a role in the immune syst processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Ses to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation .
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	18-262
Mol Weight	43.9kDa
Nature	recombinant
Protein Description	Partial

Subcellular Location	Membrane, Single-pass membrane protein
Uniprot	A1KXC4, A1KXC4
Database Links	KEGG:mmu:69169 STRING:10090.ENSMUSP00000048303 UniGene:Mm.46042
Function	May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation (By similarity).
Research Area	Others
Weight	43.9kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Mus Musculus (Mouse)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10500526	CSB-EP007972MO	1mg	$2466		Add to Cart
BHP10500526	CSB-EP007972MO	100ug	$578		Add to Cart
BHP10500526	CSB-EP007972MO	20ug	$306		Add to Cart

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