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Home / Proteins & Peptide

Recombinant Mouse EPHB1 (N-GST tag)

SKU : BHP10900338

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z600011
Description	EPHB1 is a member of the Eph family of receptor tyrosine kinases. Ligand-activated EPHB1 forms a signaling complex with Nck, paxillin, and focal adhesion kinase and induces tyrosine phosphorylation of paxillin in a c-Src-dependent manner to promote cell migration . In addition, activated EPHB1 recruits the adaptor proteins Grb2 and p52Shc and promotes p52Shc and c-Src tyrosine phosphorylation as well as MAPK/extracellular signal-regulated kinase (ERK) activation. Expression of dominant-negative c-Src significantly reduced EPHB1-dependent ERK1/2 activation and chemotaxis .
Alternative Names	Elk ; Net ; Cek6 ; Elkh ; Hek6 ; EPHT2 ; AW488255 ; 9330129L11
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Mouse
Biological Activity Comment	The specific activity of EPHB1 was determined to be 143 nmol/min/mg as per activity assay protocol.

Weight	62.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Mus Musculus (Mouse)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900338	Z600011	10µg	$314.44		Add to Cart

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