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Recombinant Mouse Complement component receptor 1-like protein(Cr1l),partial

SKU : BHP10505166

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP717575MO1
Description	Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.
Alternative Names	Complement regulatory protein Crry Protein p65
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Complement regulatory protein Crry; Protein p65
Expression Region	41-405aa
Mol Weight	44.5 kDa
Nature	Recombinant
Protein Description	Partial

Subcellular Location	Membrane, Single-pass type I membrane protein
Uniprot	Q64735, Q64735
Database Links	KEGG:mmu:12946 UniGene:Mm.301652
Function	Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.
Protein Families	Receptors of complement activation (RCA) family
Research Area	Others
Tissue Specificity	Ubiquitously expressed (at protein level).
Weight	44.5 kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 85% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Mus Musculus (Mouse)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10505166	CSB-EP717575MO1	1mg	$2466		Add to Cart
BHP10505166	CSB-EP717575MO1	100ug	$578		Add to Cart
BHP10505166	CSB-EP717575MO1	20ug	$306		Add to Cart

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