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Home / Proteins & Peptide

Recombinant Mouse Claudin-18(Cldn18)-VLPs (Active)

SKU : BHP10509504

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-MP005498MO(F3)
Alternative Names	(Claudin-18)
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein indeionized sterile water to a concentration of 0.1-1.0 mg/mL.Aliquot for long-term storage at -80°C. Solubilize for 60 minutes at room temperature with occasional gentle mixing. Avoid vigorous shaking or vortexing.
Tag	N-terminal 6xHis-tagged (This tag can be tested only under denaturing conditions)
Molecular Weight	29.1 kDa
Relevance	"Claudin 18 is a novel negative regulator of bone resorption and osteoclast differentiation." Linares G.R., Brommage R., Powell D.R., Xing W., Chen S.T., Alshbool F.Z., Lau K.H., Wergedal J.E., Mohan S. J Bone Miner Res 27:1553-1565(2012)
Source	Mammalian cell
Endotoxin Level	Less than 1.0 EU/ug as determined by LAL method.
Form	Lyophilized powder
Notes	Repeated freezing and thawing is not recommended. Store the protein at -20°C/-80°C upon receiving it, and ensure to avoid repeated freezing and thawing, otherwise, it will affect the protein activity.
Bioactivity	Yes
Expression Region	1-264aa of Isoform A2.1
Lead Time	3-7 business days
Protein Length	Full Length of Isoform A2.1

Uniprot	P56857
Gene Name	Cldn18
Function	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Research Area	Cancer
Sequence	MSVTACQGLGFVVSLIGFAGIIAATCMDQWSTQDLYNNPVTAVFNYQGLWRSCVRESSGFTECRGYFTLLGLPAMLQAVRALMIVGIVLGVIGILVSIFALKCIRIGSMDDSAKAKMTLTSGILFIISGICAIIGVSVFANMLVTNFWMSTANMYSGMGGMGGMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLTPDDSNFKAVSYHASGQNVAYRPGGFKASTGFGSNTRNKKIYDGGARTEDDEQSHPTKYDYV

Buffer	Lyophilized from a 0.2 um filtered PBS, 6% Trehalose, pH 7.4
Purity	Testing in progress.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

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SKU	Supplier No.	Size	Your price	Quantity
BHP10509504	CSB-MP005498MO(F3)	1mg	$6042		Add to Cart
BHP10509504	CSB-MP005498MO(F3)	100ug	$1140		Add to Cart
BHP10509504	CSB-MP005498MO(F3)	20ug	$570		Add to Cart

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