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Home / Proteins & Peptide

Recombinant Mouse CD45/PTPRC Protein (His & GST Tag)(Active)

SKU : BHP10301187

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSM040297
Description	A DNA sequence encoding the mouse PTPRC (Arg453-Ser1152) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
Alternative Names	PTPRC ; Ly-5
Background	The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. CD45 is found expression specifically in hemotopietic cells. CD45 consists of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. It serves as an essential regulator of T-cell and B-cell antigen receptor signaling through either direct interaction with components of the antigen receptor complexs or by activating various Src family kinases required for the antigen receptor signaling and it also can suppress JAK kinases.
Tag	His tag ; GST tag
Regulatory	RUO
Host	Baculovirus-Insect Cells
Endotoxin Level	< 1.0 EU per μg of the protein as determined by the LAL method
Nature	Recombinant

Shipping	Liquid. It is shipped out with blue ice.
Buffer	Supplied as sterile 20mM Tris, 500mM NaCl, 0.5mM GSH, 3mM DTT, pH 7.4, 10% gly
Description	Please refer to the printed manual for detailed information.
Purity	> 95 % as determined by SDS-PAGE
Expiry Date	Samples are stable for up to twelve months from date of receipt at -70℃

Immunogen Species	Mus Musculus (Mouse)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10301187	PKSM040297	100ug	$1070		Add to Cart

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