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Home / Proteins & Peptide

Recombinant Mouse B7-H4/VTCN1 Protein (aa 25-256, Fc Tag)

SKU : BHP10305227

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSM040966
Alternative Names	V-set domain containing T-cell activation inhibitor 1;B7 homolog 4;Protein B7S1;B7-H4;VTCN1;B7h4;B7s1;B7x;BC032925
Reconstitution	Please refer to the printed manual for detailed information.
Background	Mouse V-set domain-containing T-cell activation inhibitor 1/VTCN1/B7-H4 is glycosylated member of the B7 family of immune co-stimulatory proteins. B7-H4 consists of extracellular domain (ECD) with one Ig-like V-set domain and one Ig-like C2-set domain. It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation.
Reactivity	Mouse
Tag	C-Fc
Description	Recombinant Mouse B7 Homolog 4 is produced by our Mammalian expression system and the target gene encoding Leu25-Ser256 is expressed with a Fc tag at the C-terminus.
Formulation	Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Host	Human Cells
Accession Number	Q7TSP5
Endotoxin Level	< 1.0 EU per ?g as determined by the LAL method.
Mol Weight	52.7 kDa
Mw(kda)	52.7 kDa

Sequence Info	Leu25-Ser256

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by SDS-PAGE

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305227	PKSM040966	10ug	$111		Add to Cart
BHP10305227	PKSM040966	50ug	$297		Add to Cart

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