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Recombinant Mouse Aminoacyl tRNA synthase complex-interacting multifunctional protein 1(Aimp1)

SKU : BHP10503286

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP020871MO
Alternative Names	Multisynthase complex auxiliary component p43, Cleaved into the following chain:, Endothelial monocyte-activating polypeptide 2, EMAP-2, Alternative name(s):, Endothelial monocyte-activating polypeptide II, EMAP-II, Small inducible cytokine subfamily E member 1, Endothelial monocyte-activating polypeptide II ; Short name: ; EMAP-II ; Small inducible cytokine subfamily E member 1
Antigen	AIMP1
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of Cytoplasmic domain arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7 (By similarity).
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Aminoacyl tRNA synthase complex-interacting multifunctional protein 1; Alternative name(s): Multisynthase complex auxiliary component p43; Cleaved into the following chain: 1. Endothelial monocyte-activating polypeptide 2; S
Expression Region	2-310aa
Mol Weight	49.9kDa
Nature	recombinant
Protein Description	Full Length of Mature Protein

Subcellular Location	Nucleus, Cytoplasm, cytosol, Cytoplasmic vesicle, secretory vesicle, Secreted, Endoplasmic reticulum, Golgi apparatus
Uniprot	P31230, P31230
Database Links	STRING:10090.ENSMUSP00000029663 UniGene:Mm.235137
Function	Non-catalytic component of the multisynthase complex
Research Area	Cell Biology
Tissue Specificity	Highly expressed in salivary glands and pancreatic alpha cells in the adult (at protein level) (PubMed:17001013). In the embryo, expressed primarily at sites of tissue remodeling such as ganglia, developing bones and teeth (PubMed:9770485).
Weight	49.84kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Mus Musculus (Mouse)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10503286	CSB-EP020871MO	1mg	$2466		Add to Cart
BHP10503286	CSB-EP020871MO	100ug	$729		Add to Cart
BHP10503286	CSB-EP020871MO	20ug	$388		Add to Cart

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