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Home / Proteins & Peptide

Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 5(Adamts5)

SKU : BHP10503269

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP889914MO
Alternative Names	, ADAM-TS 5, ADAM-TS5, ADAMTS-5, Alternative name(s):, ADMP-2, Aggrecanase-2, Implantin, ADMP-2 ; Aggrecanase-2 ; Implantin
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period.
Source	E.coli
Abbreviation	Adamts5
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: A disintegrin and metalloproteinase with thrombospondin motifs 5; Short name= ADAM-TS 5; Short name= ADAM-TS5; Short name= ADAMTS-5; EC= 3.4.24.-; Alternative name(s): ADMP-2; Aggrecanase-2; Implantin
Expression Region	262-930aa
Mol Weight	77.8kDa
Nature	recombinant
Protein Description	Full Length of Mature Protein

Subcellular Location	Secreted, extracellular space, extracellular matrix
Uniprot	Q9R001, Q9R001
Database Links	KEGG:mmu:23794 STRING:10090.ENSMUSP00000023611 UniGene:Mm.112933
Function	Metalloproteinase that plays an important role in connective tissue organization, development, inflammation, arthritis, and cell migration. ADAMTS5 is an extracellular matrix (ECM) degrading enzyme that show proteolytic activity toward the hyalectan group of chondroitin sulfate proteoglycans (CSPGs) including aggrecan, versican, brevican and neurocan. Cleavage within the hyalectans occurs at Glu-Xaa recognition motifs. Plays a role in embryonic development, including limb and cardiac morphogenesis, and skeletal muscle development through its versican remodeling properties. Participates in the development of brown adipose tissue and browning of white adipose tissue
Research Area	Signal Transduction
Weight	77.85kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Mus Musculus (Mouse)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10503269	CSB-EP889914MO	1mg	$2466		Add to Cart
BHP10503269	CSB-EP889914MO	100ug	$729		Add to Cart
BHP10503269	CSB-EP889914MO	20ug	$388		Add to Cart

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