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Home / Proteins & Peptide

Recombinant Mouse 14-3-3 protein beta/alpha(Ywhab)

SKU : BHP10505296

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-YP875120MOa4
Description	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13.
Alternative Names	Protein kinase C inhibitor protein 1
Tag	N-terminal 6xHis-sumostar-tagged
Regulatory	RUO
Relevance	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13.
Source	Yeast
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Protein kinase C inhibitor protein 1
Expression Region	1-246aa
Mol Weight	44.1 kDa
Nature	Recombinant
Protein Description	Full Length

Subcellular Location	Cytoplasm, Melanosome
Uniprot	Q9CQV8, Q9CQV8
Database Links	KEGG:mmu:54401 STRING:10090.ENSMUSP00000018470 UniGene:Mm.34319
Function	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13.
Pathway	Hippo signaling pathway; PI3K-Akt signaling pathway; Cell cycle
Protein Families	14-3-3 family
Research Area	Neuroscience
Weight	44.1 kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 85% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer，50% glycerol

Immunogen Species	Mus Musculus (Mouse)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10505296	CSB-YP875120MOa4	1mg	$2959		Add to Cart
BHP10505296	CSB-YP875120MOa4	100ug	$694		Add to Cart
BHP10505296	CSB-YP875120MOa4	20ug	$368		Add to Cart

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