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Home / Proteins & Peptide

Recombinant M-CSF, Rat

SKU : BHP11300116

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Mfr.No.	BK0129‐10μg
Description	Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells. Interaction of M-CSF with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of several types of cancer, including breast and endometrial cancer.Recombinant Rat Macrophage Colony Stimulating Factor (M-CSF) produced in E.coli is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 155 amino acids each. A fully biologically active molecule, rrM-CSF has a molecular mass of 28 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
Alternative Names	Macrophage Colony Stimulating Factor ; CSF-1 ; Lanimostim ; MCSF ; M-CSF
Regulatory	RUO
Source	Escherichia coli.
Host	Rat
Endotoxin Level	< 0.2 EU/μg, determined by LAL method.
Biological Activity Comment	ED50 < 5 ng/ml, measured in a cell proliferation assay using Murine M-NFS-60 cells, corresponding to a specific activity of > 2×10ˆ5 units/mg.
Nature	Recombinant

Weight	28 kDa, observed by reducing SDS-PAGE.

Description	Reconstituted in ddH2O at 100 μg/ml.
Format	Lyophilized after extensive dialysis against 50mM Tris, 150mM NaCl, pH 8.0. Sterile Filtered White lyophilized (freeze-dried) powder.
Purity	> 95% as analyzed by SDS-PAGE.
Storage	Lyophilized recombinant Rat Macrophage Colony Stimulating Factor(M-CSF) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Rat M-CSF should be stable up to 1 week at 4°C or up to 3 months at -20°C.

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SKU	Supplier No.	Size	Your price	Quantity
BHP11300116	BK0129‐10μg	10μg	$188.67		Add to Cart
BHP11300116	BK0129‐10μg	1mg	$4011.11		Add to Cart
BHP11300116	BK0129‐10μg	50μg	$485.20		Add to Cart

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