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Home / Proteins & Peptide

Recombinant KGF/FGF-7, Mouse

SKU : BHP11300105

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Mfr.No.	BK0117‐10μg
Description	Keratinocyte Growth Factor (KGF) is a highly specific epithelial mitogen produced by fibroblasts and mesenchymal stem cells. KGF belongs to the heparin binding Fibroblast Growth Factor (FGF) family, and is known as FGF-7. However, in contrast to FGF-1, which binds to all known FGF receptors with high affinity, KGF only binds to a splice variant of the FGF receptor, FGFR2-IIIb. FGFR2-IIIb is expressedby most epithelial cells, indicating KGF’s roleas a paracrine mediator. KGF induces the differentiation and proliferation of various epithelial cells such as keratinocytes in the epidermis, hair follicles and sebaceous glands., KGF is also responsible for wound repair of various tissuesincluding lung, bladder, and kidney. Recombinant mouse Keratinocyte Growth Factor (rmKGF) produced in E.coli is a single non-glycosylated polypeptide chain containing 163 amino acids. A fully biologically active molecule, rmKGF has a molecular mass of 18.7 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
Alternative Names	FGF7 ; Keratinocyte Growth Factor ; Fibroblast Growth Factor-7 ; HBGF-7 ; HBGF7
Regulatory	RUO
Source	Escherichia coli.
Host	Mouse
Endotoxin Level	< 0.2 EU/μg, determined by LAL method.
Biological Activity Comment	ED50 < 2 ng/ml, measured by a cell proliferation assay using 4MBr-5 cells, corresponding to a specific activity of > 5.0× 10ˆ5 units/mg.
Nature	Recombinant

Weight	18.7 kDa, observed by reducing SDS-PAGE.

Description	Reconstituted in PBS at 100 μg/ml.
Format	Lyophilized after extensive dialysis against PBS. Sterile Filtered White lyophilized (freeze-dried) powder.
Purity	> 95% by SDS-PAGE and HPLC analyses.
Storage	Lyophilized recombinant mouse Keratinocyte Growth Factor (rmKGF) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rmKGF remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.

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SKU	Supplier No.	Size	Your price	Quantity
BHP11300105	BK0117‐10μg	10μg	$188.67		Add to Cart
BHP11300105	BK0117‐10μg	1mg	$4011.11		Add to Cart
BHP11300105	BK0117‐10μg	50μg	$485.20		Add to Cart

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