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Home / Proteins & Peptide

Recombinant IP-10/CRG-2/CXCL10, Rat

SKU : BHP11300277

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Mfr.No.	BK0318‐1mg
Description	C-X-C motif chemokine 10 (CXCL10) also known as interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10, is originally identified as an IFN-γ-inducible gene in monocytes, fibroblasts and endothelial cells. It has since been shown that IP-10 mRNA is also induced by LPS, IL-1β, TNF-α, IL-12 and viruses. Additional cell types that have been shown to express IP-10 include activated T-lymphocytes, splenocytes, keratinocytes, osteoblasts, astrocytes, and smooth muscle cells. IP-10 is also expressed in psoriatic and lepromatous lesions of the skin. Recombinant rat IP-10/CRG-2/CXCL10 produced in HEK 293 cells is a polypeptide chain containing 77 amino acids. A fully biologically active molecule, rr IP-10/CRG-2/CXCL10 has a molecular mass of 8.7 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
Alternative Names	Small inducible cytokine B10 ; CXCL10 ; 10 kDa interferon-gamma-induced protein ; Gamma-IP10 ; IP-10 ; chemokine (C-X-C motif) ligand 10 ; C7 ; IFI10 ; INP10 ; crg-2 ; mob-1 ; SCYB10 ; gIP-10
Regulatory	RUO
Source	HEK 293
Host	Rat
Endotoxin Level	< 0.2 EU/μg, determined by LAL method.
Biological Activity Comment	The EC50 value of rat IP-10/CRG-2/CXCL10 on Caˆ2+ mobilization assay in CHO-K1/Gα15/rCXCR3 cells (human Gα15 and rat CXCR3 stably expressed in CHO-K1 cells) is less than 300 ng/ml.
Nature	Recombinant

Weight	8.7 kDa, observed by reducing SDS-PAGE.

Description	Reconstituted in ddH2O or PBS at 100 μg/ml.
Format	Lyophilized after extensive dialysis against PBS. Sterile Filtered White lyophilized (freeze-dried) powder.
Purity	> 98% as analyzed by SDS-PAGE.
Storage	Lyophilized recombinant Rat IP-10/CRG-2/CXCL10 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Rat IP-10/CRG-2/CXCL10 should be stable up to 1 week at 4°C or up to 3 months at -20°C.

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SKU	Supplier No.	Size	Your price	Quantity
BHP11300277	BK0318‐1mg	1mg	$3086.67		Add to Cart
BHP11300277	BK0318‐1mg	25μg	$423.33		Add to Cart
BHP11300277	BK0318‐1mg	5μg	$173.16		Add to Cart

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