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Home / Proteins & Peptide

Recombinant IL-11, Mouse(HEK 293-expressed)

SKU : BHP11300270

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Mfr.No.	BK0311‐50μg
Description	Interleukin-11 (IL-11) is a pleiotropic cytokine that was originally detected in the conditioned medium of an IL-1α-stimulated primate bone marrow stromal cell line (PU-34) as a mitogen for the IL-6-responsive mouse plasmacytoma cell line T11. IL-11 contains no cysteine residues or potential glycosylation sites. IL-11 has multiple effects on both hematopoietic and nonhematopoietic cells. Many of the biological effects described for IL-11 overlap those for IL-6. In vitro, IL-11 can synergize with IL-3, IL-4 and SCF to shorten the G0 period of early hematopoietic progenitors. IL-11 also enhances the IL-3-dependent megakaryocyte colony formation. IL-11 has been found to stimulate the T cell dependent development of specific immunoglobulin-secreting B cell.
Alternative Names	Interleukin-11 ; IL11
Regulatory	RUO
Source	HEK 293
Host	Mouse
Endotoxin Level	< 0.2 EU/μg, determined by LAL method.
Biological Activity Comment	ED50 < 3 ng/ml, measured in a cell proliferation assay using T11 cells.
Nature	Recombinant

Weight	~21 kDa, observed by reducing SDS-PAGE.

Description	Reconstituted in ddH2O or PBS at 100 μg/ml.
Format	Lyophilized after extensive dialysis against PBS. Sterile Filtered White lyophilized (freeze-dried) powder.
Purity	> 95% as analyzed by SDS-PAGE and HPLC.
Storage	Lyophilized recombinant Murine Interleukin-11 (IL-11) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Murine Interleukin-11 (IL-11) should be stable up to 1 week at 4°C or up to 2 months at -20°C.

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SKU	Supplier No.	Size	Your price	Quantity
BHP11300270	BK0311‐50μg	50μg	$650		Add to Cart

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