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Home / Proteins & Peptide

Recombinant Human VWC2/Brorin Protein (His Tag)

SKU : BHP10300454

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH030918
Description	A DNA sequence encoding the human VWC2 (NP_055747.1) (Met 1-Met 325) was expressed, fused with a polyhistidine tag at the C-terminus.
Alternative Names	UNQ739/PRO1434 ; MGC131845 ; PSST739 ; UNQ739
Background	Brorin, also known as brain-specific chordin-like protein, von Willebrand factor C domain-containing protein 2 and VWC2, is a secreted protein which contains two VWFC domains. VWC2/ Brorin is a BMP antagonist which may play a role in neural development. It promotes cell adhesion. VWC2/ Brorin is a unique member of the chordin family. It inhibited the activity of bone morphogenetic protein 2 (BMP2) and BMP6 in mouse preosteoblastic MC3T3-E1 cells. Mouse Brorin was predominantly expressed in neural tissues in embryos and also predominantly expressed in the adult brain. In the brain, the expression was detected in neurons, but not glial cells. The neural tissue-specific expression profile of Brorin is quite distinct from that of any other member of the Chordin family. VWC2/ Brorin protein promoted neurogenesis, but not astrogenesis, in mouse neural precursor cells. VWC2/ Brorin is a novel secreted BMP antagonist that potentially plays roles in neural development and functions.
Tag	His tag
Regulatory	RUO
Host	Human Cells
Endotoxin Level	< 1.0 EU per μg of the protein as determined by the LAL method
Nature	Recombinant

Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Buffer	Lyophilized from sterile PBS, pH 7.4
Description	Please refer to the printed manual for detailed information.
Purity	> 95 % as determined by SDS-PAGE
Expiry Date	Samples are stable for up to twelve months from date of receipt at -70℃

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10300454	PKSH030918	100ug	$732		Add to Cart

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