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Home / Proteins & Peptide

Recombinant Human UBE2A Protein (His Tag)

SKU : BHP10300360

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH030787
Description	A DNA sequence encoding the mature form of human UBE2A (P49459) (Met 1-Cys 152) was expressed, with a polyhistidine tag at the N-terminus.
Alternative Names	HHR6A ; RAD6A ; UBC2
Background	Ubiquitin-conjugating enzyme E2 A (also known as HHR6A or UBE2A), encoded by human DNA repair genes HHR6A, belongs to the ubiquitin-conjugating enzymes (E2 enzymes) family and is likely to be involved in postreplication repair and induced mutagenesis. UBE2A is described as a CDK2 substrate. It is the human homologue of the product of the Saccharomyces cerevisiae RAD6/ UBC2 gene, a member of the family of ubiquitin-conjugating enzymes. In vivo, HHR6A phosphorylation peaks during the G2/M phase of cell cycle transition, with a concomitant increase in histone H2B ubiquitylation. Mutation of Ser120 to threonine or alanine abolished UBE2A activity, while mutation to aspartate to mimic phosphorylated serine increased UBE2A activity 3-fold. A mutation of UBE2A is consisdered as the cause of a novel X-linked mental retardation (XLMR) syndrome that affects three males in a two-generation family.
Tag	His tag
Regulatory	RUO
Host	E. coli
Nature	Recombinant

Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Buffer	Lyophilized from sterile PBS, 20% glycerol, pH 7.5
Description	Please refer to the printed manual for detailed information.
Purity	> 80 % as determined by SDS-PAGE
Expiry Date	Samples are stable for up to twelve months from date of receipt at -70℃

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10300360	PKSH030787	100ug	$670		Add to Cart

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