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Home / Proteins & Peptide

Recombinant Human U1 small nuclear ribonucleoprotein 70 kDa(SNRNP70),partial

SKU : BHP10505597

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP714018HU1a0
Alternative Names	RNPU1Z, RPU1, SNRP70, U1AP1
Antigen	SNRNP70
Tag	N-terminal 6xHis-tagged
Description	Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.
Regulatory	RUO
Relevance	Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	RNPU1Z, RPU1, SNRP70, U1AP1
Expression Region	1-210aa
Mol Weight	28.7 kDa
Nature	Recombinant
Protein Description	Partial

Subcellular Location	Nucleus, Nucleus speckle, Nucleus, nucleoplasm
Uniprot	P08621, P08621
Database Links	HGNC:11150 OMIM:180740 KEGG:hsa:6625 STRING:9606.ENSP00000472998 UniGene:Hs.467097
Function	Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.
Research Area	Epigenetics and Nuclear Signaling
Weight	28.7 kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 85% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer，50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10505597	CSB-EP714018HU1a0	1mg	$2466		Add to Cart
BHP10505597	CSB-EP714018HU1a0	100ug	$729		Add to Cart
BHP10505597	CSB-EP714018HU1a0	20ug	$388		Add to Cart

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