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Home / Proteins & Peptide

Recombinant Human Tyrosine-protein kinase JAK1(JAK1),partial

SKU : BHP10503113

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-YP011930HU
Alternative Names	Janus kinase 1, JAK-1, Janus kinase 1 ; JAK-1
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.
Source	Yeast
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Tyrosine-protein kinase JAK1; EC= 2.7.10.2; Alteative name(s): Janus kinase 1; Short name= JAK-1
Expression Region	850-1154aa
Mol Weight	36.9kDa
Nature	recombinant
Protein Description	Partial

Subcellular Location	Endomembrane system, Peripheral membrane protein
Uniprot	P23458, P23458
Database Links	HGNC:6190 OMIM:147795 KEGG:hsa:3716 STRING:9606.ENSP00000343204 UniGene:Hs.207538
Function	Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway
Pathway	Jak-STAT signaling pathway; PI3K-Akt signaling pathway; Necroptosis; Signaling pathways regulating pluripotency of stem cells; NOD-like receptor signaling pathway; Osteoclast differentiation; Th1 and Th2 cell differentiation; Th17 cell differentiation
Protein Families	Protein kinase superfamily, Tyr protein kinase family, JAK subfamily
Research Area	Cancer
Tissue Specificity	Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue.
Weight	36.95kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10503113	CSB-YP011930HU	500ug	$1916		Add to Cart
BHP10503113	CSB-YP011930HU	100ug	$694		Add to Cart
BHP10503113	CSB-YP011930HU	20ug	$368		Add to Cart

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