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Home / Proteins & Peptide

Recombinant Human TWEAK Receptor (TNFRSF12A)

SKU : BHP10900898

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z102525
Description	Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) is the receptor for TNFSD12/TWEAK and is the smallest member of the TNF receptor superfamily. It is composed of a signal peptide, an extracellular domain, a membrane-anchoring domain, and a cytoplasmic “death” domain, which can activate a cell’s apoptotic mechanisms. It also promotes endothelial cell proliferation and angiogenesis, and modulates cellular adhesion to matrix proteins. TNFRSF12A expression can be found in the spleen, thymus, small intestine, and colon, and can be activated by membrane-anchored or soluble versions of TWEAK.
Alternative Names	Tweak-receptor ; CD-antigen: CD266 ; Fibroblast growth factor-inducible immediate-early response protein 14
Quantity	25 µg
Regulatory	RUO
Source	E. coli
Host	Human
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method
Biological Activity Comment	The ED(50) was determined by the dose-dependent proliferation of human umbilical vein endothelial cells and was found to be <0.2ng/mL.

Weight	5.6 kDa

Format	Lyophilized Powder Lyophilized from a 0.2 µm filtered solution in PBS
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.

Immunogen Species	Homo Sapiens (Human)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900898	Z102525	25µg	$119.44		Add to Cart

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