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Home / Proteins & Peptide

Recombinant Human Tumor necrosis factor receptor superfamily member 17 protein(TNFRSF17),partial (Active)

SKU : BHP10500220

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-AP002271HU
Alternative Names	B-cell maturation protein
Pubmed Id	1396583; 8165126; 11528522; 17825416; 10493829; 15616553; 10903733; 10801128; 10973284; 10908663; 12721620; 15542592
Regulatory	RUO
Source	E.coli
Endotoxin Level	Less than 1.0 EU/μg as determined by LAL method.
Bioactivity	Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated murine B cells is no less than 40 ng/ml, corresponding to a specific activity of >2.5x10⁴ IU/mg in the presence of 100 ng/ml human APRIL.
Expression Region	5-54aa
Mol Weight	5.4 kDa
Nature	recombinant
Protein Description	Partial

Involvement In Disease	A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
Subcellular Location	Cell membrane, Single-pass type III membrane protein, Endomembrane system, Single-pass type III membrane protein
Uniprot	Q02223, Q02223
Database Links	HGNC:11913 OMIM:109545 KEGG:hsa:608 STRING:9606.ENSP00000053243 UniGene:Hs.2556
Function	Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Research Area	Cancer
Tissue Specificity	Expressed in mature B-cells, but not in T-cells or monocytes.
Weight	5.4 kDa

Buffer	0.2 μm filtered 30 % acetonitrile, 0.1 % TFA,lyophilized
Purity	>98% as determined by SDS-PAGE and HPLC.
Storage Buffer	0.2 μm filtered 30 % acetonitrile, 0.1 % TFA ,lyophilized

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10500220	CSB-AP002271HU	500ug	$4536		Add to Cart
BHP10500220	CSB-AP002271HU	100ug	$2022		Add to Cart
BHP10500220	CSB-AP002271HU	5ug	$142		Add to Cart

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